The Interleukin 6 −174 C/C Genotype Predicts Greater Rhinovirus Illness
نویسندگان
چکیده
منابع مشابه
The interleukin 6 -174 C/C genotype predicts greater rhinovirus illness.
BACKGROUND In adults and children with respiratory syncytial virus (RSV) infection, a polymorphism in the interleukin 6 (IL-6) promoter at position -174 predicts illness magnitude. In addition, polymorphisms in the interleukin 10 (IL-10), tumor necrosis factor alpha (TNF-alpha), and interferon gamma (IFN-gamma) genes are associated with immune responsiveness and the frequency of complications. ...
متن کاملThe effect of the interleukin-6 c/g-174 polymorphism and circulating interleukin-6 on fibrinogen plasma levels.
BACKGROUND AND OBJECTIVES C-reactive protein (C-RP) levels correlate with fibrinogen values and are predictive of coronary artery disease. Interleukin-6 (IL-6) strongly regulates the production of C-RP. A polymorphism (C/G-174) within the IL-6 gene has been shown to affect IL-6 gene expression and plasma concentrations. DESIGN AND METHODS In 598 asymptomatic employees of a hospital in Souther...
متن کاملcorrelation of interleukin‑6‑174 gc and interleukin‑6‑572 gc gene polymorphisms with periodontal disease in an iranian population
background: periodontal disease has a multifactorial etiology. a combination of microbial agents and environmental, habitual, systemic, and genetic risk factors is responsible for the development of periodontal disease. host immune response causes the destruction of tooth‑supporting structure and eventual tooth loss. this study aimed to assess the correlation of interleukin 6 (il‑6) ‑174‑gc and...
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The association between interleukin (IL)-6 promoter polymorphism (-174 G/C), circulating IL-6 levels and mortality in septic patients has scarcely been addressed, and then only in studies of small sample size, and a direct association among them has not been previously reported. Therefore, the purpose of our study was to determine whether this association exists. An observational, prospective a...
متن کامل-174 G>C polymorphism of interleukin 6 gene promoter affects interleukin 6 serum level in patients with colorectal cancer.
PURPOSE Experimental data suggest that interleukin 6 (IL-6) plays an important role in the development and progression of metastasis from colorectal cancer (CRC), and -174 G>C polymorphism has been identified recently in the IL-6 gene promoter. Therefore, the aim of the present study was to investigate the significance of this type of polymorphism in patients with CRC. EXPERIMENTAL DESIGN Usi...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2010
ISSN: 0022-1899,1537-6613
DOI: 10.1086/649559